Jacob S. Pickle was born in 1835 in New York.
Jacob left New York and had settled in western Michigan by the time the war had broken out, and possibly even earlier.
(By 1860 there was one John Pickle, age 25, born in New York, married to Elizabeth and with one child living in Rutland, Barry County. There there was also a Jacob Pickle, age 32, born in New York, and married to Martha and with three children living in Monroe County. Both men were born in New York, and were possibly related to one J. M. Pickle, age 50, from New York, and Robert Pickle, both living in Hastings in 1860.)
Jacob was probably working as a farmer in Hastings, Barry County when he enlisted in the Hastings Rifle Company in April of 1861. The company was disbanded shortly after it arrived in Grand Rapids and its members distributed to other companies of the Third Michigan infantry then forming at Cantonment Anderson just south of the city, and Jacob eventually enlisted at the age of 26 in Company K on May 13, 1861.
Jacob died of typhoid fever on September 8, 9 or 17, 1861, at Seminary hospital, Georgetown, DC, and was buried in the Military Asylum cemetery (Soldier's Home National cemetery), section B, grave no. 1451.
No pension seems to be available.